Synonym(s): - Eccrine tumors-ectodermal dysplasia - Keratosis palmoplantaris - cystic eyelids - hypodontia - hypotrichosis - Palmoplantar hyperkeratosis - cystic eyelids - hypodontia - hypotrichosis - Palmoplantar keratoderma - cystic eyelids - hypodontia - hypotrichosis - SSPS
Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare genetic disease - Rare odontologic disease - Rare oncologic disease - Rare skin disease Entire classification		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities - See
Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: normal Type of inheritance: autosomal recessive		External references: 1 OMIM reference - See No MeSH references
More Info - Orphanet

Gene symbol	UniProt reference	OMIM reference
WNT10A	Q9GZT5	606268

- Autosomal recessive inheritance
- Hypotrichosis / atrichia / atrichiasis / scalp hairlessness
- Nails anomalies
- Palmoplantar hyperkeratosis / keratoderma

- Absent / decreased / thin eyebrows
- Alopecia
- Anodontia / oligodontia / hypodontia
- Anomalies of eyelids, eyelashes and lacrimal system
- Premature lost of decidious teeth

- Ovary / Fallopian tube neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma)
- Skin / cutaneous neoplasm / tumor / carcinoma / cancer (excluding melanoma)